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Multi-omics profiling further supported an AD-relevant signature, including shifts in blood-based neurodegeneration markers, exposure-associated autoantibody reactivity to AD- and neuroinflammation-linked targets, and perturbations in pathways implicated in neurodegeneration 270

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

Stroke 41: 12781284, 2010

In more recent work, it has been suggested that ERG was probably first biosynthesised by anaerobes using a slightly different route that converts hercynine directly to ERG (98100) , and that was later repurposed

These results suggest a possible link between DSIP activity and processes connected to mood regulation, providing an interesting direction for research on the biological underpinnings of depression