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Keywords: Triple negative breast cancer, IB-DNQ, Rucaparib, phosphoproteomics, multiomics, mass spectrometry, DNA damage, cell cycle, transcription BACKGROUND Triple negative breast cancer (TNBC) is a highly aggressive form of breast cancer that accounts for 1525% of cases (1)

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Particularly, studies have shown that targeting ferroptosis could be a potential strategy in different cancer cell types