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[DOI] [PubMed] [Google Scholar] 168.Furukawa S, Sameshima H, Yang L, Harishkumar M, Ikenoue T

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Some protocols recommend intramuscular injection into the worked muscle ("site injection"), with the theory that local IGF-1R stimulation drives localized hypertrophy

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This approach requires medical oversight to ensure dosing, timing, and monitoring are appropriate