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Description
While the ferroptosis inhibitors liprostatin-1 and Fer-1 can reduce MASH severity by inhibiting ferroptosis

Key numbers Oxidative only: G6P Ru5P + 2 NADPH + CO Full cycle (6 G6P in): 6 G6P + 12 NADP 5 G6P + 6 CO + 12 NADPH (net 1 G6P oxidized, 12 NADPH made) Thus PPP is the cells flexible supplier of reducing power and ribose, letting any tissue match antioxidant and biosynthetic needs without leaving central carbon metabolism

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Endocr Relat Cancer 21:241252
