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Fis1 and Drp1 facilitate mitochondrial division by constricting and cutting mitochondria, whereas Opa1, Mfn2, and Mfn1 promote mitochondrial fusion by merging mitochondrial membranes

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During osteoclast differentiation, the demand for iron increases, and the expression of TFR1 is increased through posttranscriptional regulation, thereby increasing iron uptake by the cell
Depending on individual needs, doctors may recommend medication to prevent or treat osteoporosis

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