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Heres a breakdown of the two main mechanisms: 1
DFT StudyMicrochemical J
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In summary, C32E8.9 and sma-4 play a role in mediating the enhanced immune response triggered by mrps-5 RNAi

It is important to note that infants with FPIES and concomitant IgE sensitization to the inciting trigger generally have a more protracted course and are at risk for the development of IgE-mediated food allergy [1]
