side effects of vitamin b12 deficiency injections Shots And How To Treat Them Vitamin B12 | The BMJ

Degraded peptide delivers inconsistent dosing that undermines study reproducibility

It is uncommon for most healthy people to not get enough Vitamin B12 from their diet, but it can be a problem depending on your age, diet, or underlying medical conditions

Both injections and oral supplements are generally safe, but very high doses of B12 can cause side effects in rare cases, such as mild digestive issues or headaches

Darker, pigmented patches or sunspots can temporarily darken, and then peel off over a week or so, leaving normal skin

This reaction simultaneously depletes two critically important metabolic cofactors: SAM (the universal methyl donor for hundreds of epigenetic and biosynthetic reactions) and nicotinamide (the precursor for NAD+ biosynthesis via the salvage pathway)