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2023 Aug 18 [cited 2024 Nov 24];102(33):e34307

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Risk factors for B12 deficiency Without saliva, B12 will not bind to the salivas R-protein, and the bodys ability to absorb it is inhibited

doi: 10.1128/JVI.02564-13 46 SanchezRMohrI

In addition, a deficiency of vitamin B12 can cause facial signs such as hyperpigmentation (dark spots), vitiligo (white patches where skin loses color), or angular stomatitis (inflammation at the corners of the mouth)
