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However, the FDA approval of Aducanumab is controversial, with the ultimate basis of approval predicated on apparent reduction of A plaques and not inhibition of clinical disease outcome (Rabinovici, 2021)

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By inhibiting AKT1, luteolin activates the intrinsic apoptotic pathway, as evidenced by increased cleaved caspase-3, caspase-9, cytochrome c, and modulation of the Bax/Bcl-2 ratio (refer to Fig

album have been shown to have anti-hepatotoxic activity in primary cultured rat hepatocytes and possess protective effect against xenobiotic-induced liver damage in mice