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PLoS Biology 2008;6, 2853-2868

Prior to his initial neurocognitive assessment, he was experiencing seizures two to three nights per week, though there were periods of remission

Allergy asthma Proc

Ubiquitin-dependent lysosomal degradation of GPCRs and long-term desensitization GPCR ubiquitination, as shown initially for the 2 AR and the chemokine receptor CXCR4, is a critical tag that directs internalized receptors to lysosomes, although initial agonist-induced endocytosis of these receptors does not require receptor ubiquitination [70, 77]
