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10.3389/fimmu.2023.1239151 16 ChalmersJ

in males, its pro-erectile effect is secondary to central mechanisms stimulating nitric oxide production in penile tissue [3]

It sheds light on the emerging knowledge regarding the peptides, their specific receptors on brain endothelial cells, the selection of drug payloads, the design of DSIP-CBBBP, mechanisms of brain entry, and the efficiency of delivery to the brain ( On the other hand, the lack of a significant anxiolytic effect with GABA treatment raises questions about its bioavailability or receptor interactions in the specific context of the EPM test, possibly due to differences in the route of administration, dosage, or the animal models specific pathology

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Eicosanoid biosynthesis via these three pathways has been implicated in the pathogenesis of AD, but the underlying molecular mechanisms remain largely elusive