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Other assessments included changes in laboratory parameters (including but not limited to haematology and biochemistry), and physical examination, vital signs and ECG

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Common symptoms include: Extreme fatigue that is not relieved by rest Post-exertional malaise: worsening of symptoms after physical or mental activity Sleep problems: unrefreshing sleep, insomnia, or other sleep disturbances Cognitive difficulties: problems with memory, focus, and concentration (often referred to as "brain fog") Muscle or joint pain Headaches Sore throat Tender lymph nodes Dizziness that worsens with moving from lying down or sitting to standing Causes and Risk Factors The exact cause of CFS is unknown, but it is believed to result from a combination of factors: Genetics: A family history of CFS or other autoimmune diseases can increase the risk