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Description
The principle of combining a systemic agent with a localized one is a popular strategy

These immunology drugs (and others like AbbVies Skyrizi , Roches Ocrevus , etc.) are all top earners

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Comptes rendus hebdomadaires des sances de l'Acadmie des sciences (in French)
This morning 1/26 I started experiencing the same redness & itching described above