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In mice, 3 weeks of CoQ 10 supplementation at a dose of 2.81 mg/g of diet was able to attenuate oxidative damage to proteins in liver in aged mice [165]
NSBSO showed GSH-dependent cytotoxicity and depletion of intracellular GSH
The first and second principal components (PC1 and PC2), accounting for 58.7% and 21.2% of the total variance, respectively, explained approximately 80% of the total variance
963 The main challenge of oligonucleotide therapy is to achieve effective and targeted delivery to tissues and cells
Our experimental design and modeling results, which considered smooth continuous gradient stimuli, carry such stimulus history, and with few assumptions, our model is mathematically analogous to the adaptivethreshold model (A detailed mathematical derivation is found in Appendix Note S1 part 5)
