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Description
Metabolic transit of dietary Methylglyoxal
In the first step, glutamate reacts with cysteine to form -glutamylcysteine under the catalysis of the rate-limiting enzyme, -glutamylcysteine ligase (GCL)
While the distribution (measured in unit body weight) of GSH in hearts skeletal muscle and brain is not as high as in other organs, the excretion of GSH via these organs is slower
Sprecher DL, Massien C, Pearce G, Billin AN, Perlstein I, Willson TM, Hassall DG, Ancellin N, Patterson SD, Lobe DC, Johnson TG
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