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Indications Carence en vitamine B12 Anmie pernicieuse Neuropathie secondaire Utilisation Adultes : Carence en vitamine B12 sans complication clinique (par exemple anmie pernicieuse et malabsorption) Par injection : Voie orale : Dose initiale : administrer 1 ampoule (1mg) par jour ou 3 ampoules par semaine, renouveler en fonction des rsultats hmatologiques

They may help with pain management and slow further degeneration, but they cannot rebuild a destroyed joint

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Vitamin B 12 deficiency, like folate deficiency, may lead to decreased synthesis of methionine and S-adenosylmethionine (SAM), thereby adversely affecting methylation reactions