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45 The present findings suggest a potential homeostasis in the folate system that is maintained in differing UVR environments via folate gene epistasis

J Clin Endocrinol Metab 71:1382, 1990

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By contrast, disruption of the Arf1-mediated lipolysis pathway or the acetyl-CoA carboxylase 1 (ACC1)-mediated de novo fatty acid synthesis pathway resulted in a marked decline in ISCs 7,18

Finally, although this study focused on a single induction protocol, variations in differentiation methods across research groups may affect maturation timelines, limiting the direct applicability of findings to alternate protocols