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However, the presence of treatment-resistant cases and the limited efficacy of the drug in treating negative symptoms and cognitive dysfunction make it difficult to explain the mechanisms of schizophrenia through the dopaminergic system alone (Correll and Schooler, 2020)

Another example is the use of in situ oxygen generation, such as by Coronel et al., where, by using calcium peroxide encapsulated in polydimethylsiloxane tablets, oxygen was raised from 0.1 mmHg to 214 mmHg, resulting in reduced anaerobic glycolysis and stimulating insulin release in pancreatic islets
doi: 10.1002/mats.201900046

POR: poor ovarian response

These shorter peptide fragments aim to reproduce specific structural features of the BDNF-TrkB binding interface
