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doi: 10.3945/jn.109.109785, PMID: [DOI] [PubMed] [Google Scholar] 114.Tarkowski E, Andreasen N, Tarkowski A, Blennow K

Furthermore, propionate and butyrate support peripheral regulatory T-cell production [132], while propionic and butyric acids raise tyrosine hydrolase gene expression, which outcomes in higher dopamine to noradrenaline conversion, important neuromodulators that regulate the fronto-striato-cerebellar circuits [133]

Metabolic pathways in T cell fate and function

Although some findings have reached statistical significance, the magnitude of the observed correlation is weak, indicating that the relationship between the variables is limited in this context

The research to date shows a relatively favorable safety profile in limited human studies, but long-term safety and large-scale clinical trials are lacking
