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Having observed the trajectory of hundreds of patients, from high-performance athletes to executives just trying to buy back a decade of vitality, a clear pattern emerges
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Serious long-term complications of diabetes mellitus include cardiovascular disease, chronic renal failure and retinal damage [7-10]

In vitro , GSH-deficient hepatocytes show upregulated mRNA levels of DNA methyltransferase, Tet2, and Tet3, along with increased Dnmt activity (5-mC) and global DNA methylation levels
