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Elevated homocysteine and aberrant FOCM have also been reported in Amyotrophic Lateral Sclerosis, Multiple Sclerosis, and Huntingtons disease and are associated with neuroinflammation, demyelination, neuronal loss, and severe disease phenotypes in these conditions

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It is commonly prescribed for individuals with pernicious anemia, certain gastrointestinal disorders, or dietary deficiencies that impair B12 absorption