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There was no change even after adjusting for a history of COVID-19 or infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
for MetS and T2D), and because exercise is one of the most potent IGF-1 synthesis/freeing mechanisms, it seems logical to correlate them and establish IGF-1 as a target for future options in the multifactorial treatment for metabolic syndrome
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