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Mechanistically, PD-1 inhibitor targets cardiac ECs, leading to ROS accumulation, which causes weakened EC-CF crosstalk and EndMT occurrence

Therefore, spirulina is considered a safe and effective adjuvant therapy for reducing the occurrence of adverse effects caused by MTX

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Using brain imaging, authors have shown that patterns of brain activity expressed during training on a serial reaction time motor task reappear during subsequent REM sleep [26], Functional Magnetic Resonance Imaging (fMRI) has also been used to compare patterns of brain activation before and after a night of sleep