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11 It contains several chemical groups such as hydroxy and carboxy to which other components can be conjugated

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A modest upregulation of the ERK pathway was more apparent in serum-starved, low-nutrient conditions (1% FCS, 2 mM Glucose) for the G12V and G12D cell lines (Figure S1D), suggesting that these mutants are more capable of sustaining this signalling cascade than the others in limited nutrient and growth factor conditions

10.1074/jbc.M111.294785 J Biol Chem