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P.et al (1989)

Beyond NMDA receptors: homeostasis at the glutamate tripartite synapse and its contributions to cognitive dysfunction in schizophrenia

This reduction correlated with impaired motor function and the development of compulsive drug-seeking behaviors ( MRI studies have further identified gray matter atrophy in the prefrontal cortex, medial cingulate gyrus, and hippocampus, regions that are critically involved in memory, decision-making, and emotional regulation ( Magnetic resonance spectroscopy provides complementary biochemical evidence of METH-induced neurotoxicity

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