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In contrast, deficiency in genes involved in direct contact between lipid droplets and peroxisomes ( SPASTIN ( spas-1 in nematodes) and ABCD1 ( pmp-4 in nematodes)) 84 did not uncouple organelle number (and increased both organelles concomitantly
That situation normal or high serum B12 with elevated MMA is what researchers now call functional B12 deficiency, and it is far more common than most clinicians recognize
2004 Mar;9(1):4-16

[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Liepinsh E, Makrecka M, Kuka J, Cirule H, Makarova E, Sevostjanovs E, Grinberga S, Vilskersts R, Lola D, Loza E, et al
2011;3:72ra18