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Lapatinib, Ferrostatin and Liproxstatin-1 according to the present computational study were capable to cross the BBB and therefore could activate the central GPx4

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Abiotic stresses generally result in overproduction of reactive oxygen species (ROS) such as singlet oxygen ( 1 O 2 ), superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH)

doi: 10.1016/j.neuron.2019.11.023 217 SuraL.ZmaV.MarsakovaL.HynkovaA.BarvkI.VlachovaV