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In summary, we found that PRKN gene expression contributes to the network of available thiols in the cell, including by parkins participation in glutathione recycling, which involves a reversible, posttranslational modification at select cysteines

Iodine status worldwide: WHO global database on iodine deficiency(2004)

Int Clin Nut Rev

Nrf2 activators Nrf2 signaling is implicated in various oxidative stress-related diseases, such as neurodegenerative diseases [209, 210], CVDs [211], diabetes [14], and cancer [212]

The HPV16 E7 oncoprotein directly suppresses the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway, significantly reducing the expression of genes that encode type I interferon and pro-inflammatory proteins, hence facilitating immune evasion in several HPV-related tumors in murine models (Luo et al., 2020)