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10.1161/CIRCRESAHA.110.217117 27 GianazzaE.BrioschiM.Martinez FernandezA.CasalnuovoF.AltomareA.AldiniG.et al (2021)

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Therefore, we need to explore the resistance mechanism of sorafenib and novel treatments against HCC, such as c-Met and downstream signaling pathway inhibitors ( Hepatocyte growth factor (HGF) and its high-affinity receptor, mesenchymal epithelial transition factor (c-Met), are closely related to the onset, progression and metastasis of multiple tumors

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