glutathione peroxidases and redox-regulated transcription factors in Cellular Redox Homeostasis: Association with the Excitatory Amino Acid Carrier 1 (EAAC1) Extracellular Glutathione Peroxidase GPx3 and

Oxidative stress occurs when you have too many reactive oxygen species (ROS) and not enough antioxidants to neutralize them

Pain 153 , 18151823 (2012)

Its central role in buffering intracellular iron and protecting cells from oxidative stress positions it as a potential vulnerability in aggressive brain tumors, such as GBM and MB

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