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Activation of the JNK1 pathway results in increased firing by AgRP neurons and results in leptin and insulin resistance in these neurons as well as in peripheral tissues (Tsaousidou, et al

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21 Furthermore, age is not a potentially risk factor because patients older than 50 years are exposed to a 2 times higher risk, approximately, of major complication of a postsurgical surgical-site infection, and in this study, the subjects were under this age

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doi: 10.1083/jcb.200201081 50 GoodwinC