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ATFS-1, a key regulator of mitochondrial UPR, increases the expression of SKN-1 and the chaperones, such as hsp-6 and hsp-60 , in response to mitochondrial disturbances 64,65
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Systemic platinum exposure at 120 mg/m 2 was 3.8% of that reported for IV for 2 h of single-dose oxaliplatin at 130 mg/m 2 (Shirao et al., 2006)

Nanodelivery of biologically active agents is a blossoming field at the intersection of materials science, engineering, medicine, and chemistry

doi: 10.1007/s10545-017-0063-1 50 MacKayMBKravtsenyukMThomasRMitchellNDDursunSM
