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ISH analysis revealed an almost complete disappearance of Plp- and Mog- positive (to the level of 6% and 3% of control respectively) and weak Mbp- positive (-5% for control) mature OLs only 3.5 days after the onset of CPZ feeding

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Human primary cell-derived liver organoid (tissue-derived) The generation of liver organoids from primary cells derived from human liver tissue represents a promising and rapidly advancing research area

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Specifically, it consists of amino acids 176-191 from the growth hormone molecule, plus an additional tyrosine residue at the N-terminus