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All cache lines have a prediction value, the RRPV (re-reference prediction value), that should correlate with when the line is expected to be reused

Sehgal P, Colombel JF, Aboubakr A, Narula N

To this end, although the altered expression of ion channels and neuronal excitability in DRG neurons might be a common CIPN pathophysiology, a more systematic approach is necessary for the identification of key upstream regulators causing such transcriptomic changes that might serve as better therapeutic targets for CIPN

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