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Therefore, a competition for shared biosynthetic pathways between n-3 and n-6 fatty acids and the opposite systemic effects of these lipids might modulate the final action of eCBs in a range of tissues

[[Cited 2018 September 18]]

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"Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis." Clinical Nutrition ESPEN

Interestingly, NAC did not alter cue-induced reinstatement in female rats regardless of their estrous cycle phase, which may suggest NAC sex-specific efficacy and some limitation in its use [41]