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10.3390/cells9030767 Cells Summary Keywords Friedreichs ataxia, frataxin, Nrf2, PIP5K1, cytoskeleton, glutathione Citation Smith FM and Kosman DJ (2020) Molecular Defects in Friedreichs Ataxia: Convergence of Oxidative Stress and Cytoskeletal Abnormalities

Briefly, as described (42), passage obstruction scored 03 (according to the loop diameters ratio close to anastomosis, loop diameters orally/loop diameters aborally = 1 passage is normal (score 0), between 1 and 1.33 is the sign of mild obstruction (score 1), between 1.33 and 1.66 is moderate obstruction (score 2), and more than 1.66 is severe obstruction (score 3))

GSH participates in disposing of ROS both indirectly and directly by neutralizing H 2 O 2 , O 2 , and OH, among others [42,43]

Aging 32, 19641976

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