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ONOO is a highly reactive molecule

For between-group differences for change over time General Linear Model for repeated measures was used with Group (HD versus LD) and Gender as between subjects factor, and Measurement (baseline versus week 24) as repeated measures factor

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This geometry is thought to influence the redox behavior of the bound copper, potentially allowing it to participate in both oxidative and reductive cellular reactions.[1] DAHK-Cu's coordination behavior differs because of its N-terminal aspartyl residue, which can contribute carboxylate-mediated chelation alongside histidine-imidazole binding