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UV exposure induces molecular cascades that alter melanocyte biology and change its morphology, proliferation, survival, and melanogenesis [3]

According to Schafer and Buettner (2001), the ratio of GSH to GSSG reveals the redox status of cell (Schafer and Buettner, 2001) Therefore, the reduced levels of GSH peroxidase and GSH-S-transferase determine the defense mechanism against ROS (Aoyama, 2021)