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Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research

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Precauciones de uso Uso interno No sustituye a una dieta equilibrada y variada ni a un estilo de vida saludable

Moreover, a percentage of patients ranging between 7 and 25%, depending on different dosage, experience adverse events upon PDE5i treatment [59, 60], sometimes manifesting as of moderate or severe entity, the most frequent of which comprise flushing, headache, dyspepsia, back pain, myalgia, dizziness, and rhinitis [10], although discontinuation rates owing to adverse events of PDE5i is generally relatively low, and comprised between 3 and 5% of patients [61]

The aim of the current review is to focus on the pathogenic mechanisms of chronic fatigue and CFS and potential of polyphenols to fight against chronic fatigue, citing data from both preclinical and clinical studies