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NaB also suppresses the induction of TLR-4 and CD14 mRNA expression in the liver and TLR2 in the colon, improves cytokines and decreases Kupffer cell activation (35)

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10.3390/nu14010091 199 RusuM

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Furthermore, supplementation with TCA cycle intermediates -KG and succinate reversed the rescue effect of anaplerosis inhibition and induced lipid peroxidation-driven cell death, even in CAMA-1 cells, which are otherwise resistant to cystine deprivation, suggesting that differential sensitivity between TNBC and luminal cells may stem from their distinct glutamine metabolic flux