glutathione pathway brain Role of cycle and the pentose phosphate in the The glutathione system in Parkinson's

Individuals 60 years and older have lower plasma GSH levels and increased oxidative stress (Samiec et al., 1998)

They are subject to post-translational modifications and have an extensive interactome, particularly with other signalling proteins

In functional medicine, we look at functional components of health and measure blood and urinary biomarkers for functional deficiencies of key nutrients such as B12

The enzyme Kynurenine aminotransferase (KAT) could be involved too, for instance in the production of KYNA and XA, this last being a KYN shunt metabolite also endowed with CNS activities and signaling properties (140, 141)

The Roles of Vitamin C in Skin Health, PMC