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Such observations raise the question as to why D-2HG only acts as an oncometabolite in specific genetic backgrounds and highlights the need to further study endogenous D-2HG metabolism in both healthy tissues and disease models

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For signals that match more than one chemical isomer indistinguishable by the LC-MS method, potential compound names are presented, separated by either or or /

For example, SM and GluCer are present in concentrations that are 1-2 order of magnitude higher than those of Cer, therefore small changes in these compounds can result in profound changes in ceramide

New Insights into the Activities of D-Chiro-Inositol: A Narrative Review