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How to Rationally Approach Supplementation for Sleep, Hormone Support, and Cognitive Enhancement Sleep Huberman suggests that if youre thinking about supplementation for sleep, you first need to optimize your behavioral and nutritional protocols, such as avoiding caffeine after 2 pm and avoiding food two hours before bed, as these can disrupt the architecture of sleep. Once these protocols are met, Huberman says you need to ask yourself a few questions

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[DOI] [PMC free article] [PubMed] [Google Scholar] Nishida N, Yano H, Nishida T, Kamura T, Kojiro M, 2006

doi: 10.1016/j.jsxm.2018.12.002

Furthermore, administration of L-carnitine substantially altered the effects of TRZ and markedly reduced the expression of autophagy-related genes such as Beclin1, Autophagy Related Gene 5 (ATG5), and the inflammatory mediator TNF- in comparison to the TRZ treated group (Khedr et al