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Irvine BD
PubMed, Harari, Ral, et al
reported that shRNA-mediated ATG3 deletion impaired the autophagy function of AML cells, leading to the upregulation of glycolysis, lactate production, and mitochondrial metabolism in AML cells
It is a story about the blind spot between chemical purity and real world performance, and about how a vial can pass standard testing while still breaking down at the point of use
