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We measured the global acyl-CoA content in the Gly and CKO groups and showed that PRMT1 knockdown in TECs increased acyl-CoA content, indicating increased fatty acid metabolism (Fig

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In liver tissue of high-fat diet-induced obese mice, FGF21 treatment augments expression of the immunosuppressive gene IKBKE and reduces expression of the pro-inflammatory gene IL-18 , independent of FGF21-induced weight loss (101)