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Thus pre-treatment with L-arginine counteracted the antidepressant-like effect of imipramine, venlafaxine and bupropion (Krass et al., 2011), while inhibition of nitric oxide levels within the hippocampus can induce antidepressant like effects (Joca and Guimaracs, 2006)
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[18] Then, the thiolate anion S 48 interacts, through non-covalent contacts, with the flavin ring near the 4a position
