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Thyroid Dysfunction Uncontrolled thyroid disorders may heighten susceptibility to side effects, especially those affecting metabolism or cardiovascular function

Abstract The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine

G., Zhu X

Apparently this is a common side effect of the Moderna Vaccine

If you present recurrent pain to your medical team and are only offered cortisone shots, it might be time to look into alternatives