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In some organisms such as fungi, the acetate is used in the glyoxylate cycle for gluconeogenesis and formation of carbohydrates

This also means that Rhodiola rosea can affect different people very differently

Eur Neuropsychopharmacol 23:12191225 Besteher B, Machnik M, Troll M, Toepffer A, Zerekidze A, Rocktaschel T, Heller C, Kikinis Z, Brodoehl S, Finke K, Reuken PA, Opel N, Stallmach A, Gaser C, Walter M (2022) Larger gray matter volumes in neuropsychiatric long-covid syndrome

Therefore, a greater understanding of how the environment affects the susceptibility to disease in some but not all APOE4 carriers requires more targeted and personalized approaches

& de Meyer, R