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The near-complete absence of free copper in the bacterial cytoplasm is maintained through the coordinated action of copper chaperones, copper storage proteins, and low-molecular-weight thiol-containing compounds (Hofmann et al

High saccharin rats are more likely to consume sweets and cocaine and are more vulnerable to the negative emotional effects of morphine withdrawal (48, 49)

80 demonstrated that this indole reduced LPS-induced inflammation and thus NLRP3 inflammasome formation in mouse adipose tissue by acting on the expression of inflammasome genes, including NLRP3, ASC, and thereby caspase-1 and IL-1

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The updated proposal includes autophagy as another hallmark owing to its relevant role in regulating other hallmarks, such as DNA repair and nutrient sensing/metabolism [220]