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doi: 10.1016/j.phrs.2022.106161, PMID: [DOI] [PubMed] [Google Scholar] 76

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus

Further studies have demonstrated that Kupper cells and hepatocytes act as a major source of circulating pro-inflammatory cytokines, including TNF-, IL-6 and proteolysis inducing factor, in cancer cachexia, via the NF-B- and STAT3-dependent signaling pathways (8), or the cyclooxygenase-2 (Cox2)/prostaglandin E2 (PGE2) pathway (9)

Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion

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